Cytokeratin 19 (CK-19) is a general marker of epithelial cells that is strongly expressed in epithelial but not in mesenchymal cells. Increased expression is seen during epithelial embryogenesis, tissue regeneration, tissue repair, tissue development, and carcinogenesis. CK-19 has been extensively studied as a potential marker for the detection of circulating tumor cells (CTC) in a variety of epithelial cancers. It is a cytoskeletal component present in normal and cancerous epithelial cells. It is expressed in 90% of invasive breast cancer tissue and thus, has been extensively used for the detection of breast cancer cells in mesenchymal tissues. It is probably the most sensitive and reliable tumor marker for the detection of CTC in patients with breast cancer.
The list of innovative products comprises RT-qPCR-based tests for the quantification of CK-19 mRNA in RNA samples.

Detecting Rare Cells in blood and other body fluids can be a real challenge. OncoLab provides research tools that make hunting for rare cells, such as circulating tumor cells (CTC), circulating endothelial cells (CEC), or circulating stromal cells (CSC) a simple diagnostic test.
OncoLab’s Circulating Rare Cell (CRC) tests are based on fluorescent immunostaining of rare cells after enrichment from blood samples. State-of-the-art biomarkers coupled with enhanced scanning optical systems powered by artificial intelligence enable convenient and efficient research of CRC.
The list of products comprises special blood collection tubes, tools and reagents for cell purification, proprietary immunofluorescent cocktails for staining (IF), tools and general use reagents for preparing cytology slides, microscope imaging, and image analysis.